A high degree of cardiovascular remodeling amongst treated type 2 diabetics is associated to the high nighttime BP and/or glucose values    High nighttime BP and/or glucose values among treated type 2 diabetes were associated with a high degree of cardiovascular remodeling.

Reinforcement of an antihypertensive combination therapy as well as the guidance of lifestyle modification for resistant hypertensives with diabetes, CKD or metabolic disorders    When the goal BP of <140/90 mm Hg was applied to all patients, the prevalence of resistant hypertension had decreased to 10.2%. Moreover, patients with resistant hypertension were characterized by a significantly higher BMI, triglyceride, uric acid, diabetes and lower HDL cholesterol, eGFR levels vs. those without resistant hypertension.

GLP-1 analogs improve glycemic control and loss of weight via the reduction of the sitting SBP: A meta-analysis of 13 trials    The overall effect on SBP with GLP-1 was -2.362 mm Hg

A higher Cardio-ankle vascular index in hypertensives with diabetes reliably evaluates the arterial stiffness index of macro- & micro-vascular complications    Cardio-ankle vascular index reported to be significantly higher in hypertensives with diabetes had positive correlations with age, systolic blood pressure, pulse pressure, fasting plasma glucose, HbA1c in the entire study group.

Monitoring of Obese Hypertensive patients upon lifestyle modification    Difference averages for each variable such as anthropometric, hemodynamic, autonomic nervous system, endothelial dysfunction, metabolic and lipid profile between before and after lifestyle modification were significant.

Insulin Resistance and 10 Year Risk of Cardiovascular Disease in Elderly Hypertensives Patients    To evaluate total cardiovascular disease risk in elderly patients with arterial hypertension in relation to plasma insulin levels under complex antihypertensive treatment with including atorvastatin.

Uric Acid Levels Are Associated with Left Ventricular Hypertrophy in Patients with the Metabolic Syndrome    To evaluate the association between serum uric acid levels and left ventricular mass, and the independence of this association of confounding factors, such as the metabolic syndrome, renal function or an inflammatory state, in a large group of essential hypertensive patients, who had never been treated with allopurinol or diuretics.

Overweight and mildly obese patients have less severe CAD in comparison to patients with ideal BMI    There was a presence of a paradoxical decrease in the median Coronary Artery Disease Severity Score with the increase in BMI.

BMI does not play a significant role in radiation exposure to the operator using transradial approach for coronary interventions    Left radial approach than with right radial approach has a safer profile with decreased operator radiation irrespective of the patient’s BMI

Femoral access in underweight women and not in women with normal or high BMI has worse bleeding outcomes than radial access    There existed similarities in the bleeding odds between the access sites in obese women and the highest odds of bleeding were reported amongst the underweight women. Moreover, higher chances of bleeding with femoral access in all women than radial access.

Safety and feasibility of an early follow- up of gastric artery embolization    Gastric artery embolization may become a less invasive and effective method for treatment of obesity.

A urinary C-peptide creatinine ratio > 0.2nmol/mmol is a reliable indicator of retained endogenous insulin secretion    A shorter time to insulin treatment and lower BMI were reported among those with confirmed absolute insulin deficiency vs. enrollees with a urinary C-peptide creatinine ratio >0.2 nmol/mmol.

An initial extent of ß-cell incompetence is the main predictor of the metabolic outcome    Restoration of the peripheral insulin sensitivity had occurred early after surgery and similarly amongst the remitters and non-remitters, which had indicated at the weight-independent effect of the operation.

30 days of resveratrol supplementation shows no effect on the fasting or postprandial incretin hormone plasma levels in obese individuals but suppresses postprandial glucagon responses    An absence of an impact on fasting plasma concentrations or postprandial plasma responses (area under curve values) of glucose-dependent insulinotropic polypeptide or glucagon-like peptide-1 with Resveratrol supplementation.

Blood glucose and plasma insulin profiles after bolus insulin infusion by a patch pump vs. a conventional pump, directly after placement and after Day 3 of use    Lower postprandial glycemic excursions on Day 3 of catheter wear time but showed similarities between patch pumps and conventional pumps.

HbA1c is an independent risk factor for the severity of angiographic coronary artery disease in patients with prediabetic state    There existed a significant association between HbA1c group and the Gensini score. Notably, a significantly higher Gensini score was reported in group with 6.0% < HbA1c < 6.5% vs. group with HbA1c < 5.5% and group with 5.5% < HbA1c < 6.0%.

CABG is strongly recommended in diabetics with multi-vessel disease over DES PCI    CABG was shown to be superior to multi-vessel disease PCI with DES in terms of a decreased overall death, non-fatal myocardial infarction, and repeat revascularization at the expense of increase in stroke risk.

Circulating levels of CD31+EMP are not predictive of development of contrast-induced nephropathy in diabetics undergoing coronary angiography    Insignificantly higher circulating CD31+EMP levels were reported amongst the patients with contrast-induced nephropathy vs. those without.

Independent associations of the lack of diabetes and lower baseline A1C with 5-yr mean A1C <6.5%: the success and baseline predictors of maintaining glycemic control in the 5 year old ORIGIN Trial    A more likelihood for a maintenance of mean A1C <6.5% after adjustment for other independent predictors was reported with glargine use (OR: 2.98) than standard care.

An elevated fibrinogen 345 mg/dl in diabetics rather than systemic inflammation and platelet reactivity is an independent predictor of CK-MB periprocedural myocardial infarction post clopidogrel pretreatment and elective PCI    Higher CRP > 0.5 mg/dl, platelet count, VerifyNow result and lower platelet inhibition were all reported amongst diabetics with fibrinogen 345 mg/dl. Furthermore, there existed an association between CK-MB >3 X ULN in diabetics and only fibrinogen 345 mg/dl.

A substantial difference in the glucose metabolism between kidney transplant recipients and non-transplant individuals    An impaired insulin secretion appeared to be the predominant pathophysiological feature amongst stable kidney transplant recipients, following transplantation.

The sensitivity and specificity of an administrative definition of diabetes vs. self-reported diabetes vs. by self-report and/or glucose testing for the estimated prevalence of undiagnosed diabetes    The prevalence of total diabetes (physician-diagnosed and undiagnosed) was found to be 13.4% (range: 11.7–15.0%) which indicated that nearly 40% of diabetics were undiagnosed.

An elevated ET-1-mediated vasoconstrictor tone in adults with impaired fasting blood glucose concentrations, independent of other cardiometabolic risk factors    A significantly greater (∼20%) increase in forearm blood flow was elicited in the impaired fasting glucose adults by a selective ETA receptor blockade vs. normoglycemia controls.

Treatment intensification with IDeg is an effective, well-tolerated alternative to that of an addition of a second or third oral antidiabetic drug for patients who are unable to achieve good glycaemic control on oral antidiabetic drugs    Higher rates of overall confirmed hypoglycemia had been reported with IDeg than with sitagliptin. Notably, an achievement of HbA1c < 7% (<53 mmol/mol) was reported by 41% IDeg vs. 28% sitagliptin patients.

An exposure to maternal diabetes in utero might not be an important determinant of short-term β-cell function decline in youth with type 1 or type 2 diabetes    The effect of in utero exposure on fasting C-peptide was not modified by diabetes type. Moreover, there existed no correlation between the exposure to maternal diabetes and the fasting C-peptide decline in youth with type 2 or type 1 diabetes.

The associations of a previous preeclampsia and mean arterial blood pressure of > 95 mmHg in essential chronic hypertensive women to increased risks of superimposed preeclampsia    There existed associations of previous preeclampsia and mean arterial blood pressure of > 95 mmHg with an increased risk of superimposed preeclampsia.

An exaggerated effect of GLP-1 in type 2 diabetics after RYGB is of a major significance in the improvement in β-cell function and in the control of glucagon release and glucose tolerance    Improved glucose tolerance, doubled β-cell glucose sensitivity, a greatly increased GLP-1 response and an augmented glucagon secretion were all reported after RYGB.

Efficacy of 24-week acarbose treatment in newly diagnosed T2D patients    There existed association between the 24 weeks of acarbose monotherapy in newly diagnosed patients with T2D and significantly increased levels of both fasting and postprandial GLP-1 as well as significantly increased nitric oxide levels and nitric oxide synthase activity.

An association between C allele and a higher prevalence of impaired fasting glycemia and/or type 2 diabetes    There existed an association of the lactase persistence genotype with a higher BMI in a longitudinal study.

Independent associations of only liver enzymes with metabolically healthy but obese phenotype    Significantly lower concentrations of AST and ALT had been reported amongst metabolically healthy but obese individuals vs. metabolically abnormal obese subjects, despite similar vitamin D levels.

The effectiveness of a sweat monitoring patch for precise AUC measurement using minimally invasive interstitial fluid extraction technology    A good correlation existed between interstitial fluid glucose AUC measurements using minimally invasive interstitial fluid extraction technology.

Respiratory/sleep disturbances appeared to be the modulators, as superimposed on blood glucose levels determined by other factors    High correlations of the three respiratory indexes and the number of nocturnal awakenings existed with the coefficient of variation of the fasting blood glucose recorded over the 7-day period at p < .005 level

Associations between dietary glycemic index and glycemic load and changes in body composition measures during adolescence    An independent association existed between the dietary glycemic index at age 12 yrs and an increased change in fat mass index between the ages 12 and 15 yrs, while dietary glycemic load showed no association with changes in any of the body composition measures examined.

Safety and tolerability of a once-daily linagliptin over 1 year and as an effective add-on therapy vs. metformin    There were occurrences of significant reductions in HbA1c levels throughout the study period for the background therapy groups that received linagliptin. Also, the decline in HbA1c levels between linagliptin and metformin groups when administered as an add-on therapy to α-glucosidase inhibitors or sulphonylurea was non-distinguishable.

A short-term, low-dose thiazolidendione treatment improves insulin sensitivity of lipolysis and hepatocellular lipid content without an influence upon muscle and liver insulin sensitivity    The metabolic pioglitazone + nateglinide action in T2DM appeared to be primarily mediated via a decline in hepatocellular lipid content associated to a greater sensitivity of lipolysis to insulin.