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HYPOS-1 study: Severe and symptomatic hypoglycemia in T1DM patients   
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Incidence rate ratio is significantly higher among women or patients with better education, or shorter duration or on pumps.
Impact of sitagliptin on counterregulatory and incretin hormones during acute hypoglycaemia in T1DM patients   
Sitagliptin does not have any affect on glucagon or adrenergic counterregulatory responses in T1DM patients.
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Association of glucose fluctuations with oxidative stress in T1DM children in different phases   
There exists a positive association between glucose fluctuations and oxidative stress in T1DM patients in different phases.
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Correlation between thyroid function, autoimmunity and metabolic derangement at the onset of T1DM   
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Antithyroid antibodies evaluation at T1DM onset may be helpful to define patients at higher risk of developing hypothyroidism.
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Heart failure screening in patients with type 2 diabetes   
Based on the clinical model, the diagnostic screening score has good discriminative properties applying a cut-off of 3 points (24.7% risk of HF) with 70.8% sensitivity, 79.0% specificity, 87.6% negative predictive value and 56.4% positive predictive value.
     
Therapeutic benefit of proton pump inhibitors for diabetes mellitus   
There is no reduction in A1C levels with proton pump inhibitor treatment in patients with type 2 diabetes.
Treating diabetic foot ulcers that are complicated by major cardiac events   
The most common presentation of electrocardiography for MACE is ST-T segment abnormality at rest.
Impact of hypothermia and diabetes mellitus on survival outcomes after out-of-hospital cardiac arrest   
DM modified the effect of mild therapeutic hypothermia on survival and neurological outcomes for out-of-hospital cardiac arrest survivors.
Glyburide versus insulin in women with gestational diabetes mellitus   
Glyburide can effectively and safely control glycemic index in women with gestational diabetes mellitus.
Plasma Abscisic Acid in Response to Oral Glucose Load in women with T2DM and gestational diabetes   
Elevated plant hormone abscisic acid has a beneficial affect on glycemic control.
Treating proliferative diabetic retinopathy with navigated panretinal photocoagulation   
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The ability to use long pulse duration navigated pattern treatments broadens therapeutic options for PRP in proliferative diabetic retinopathy.
Relationship between second and third trimester glycemic control and adverse outcomes in pregnant T1DM women   
There is a significant increase in LGA with an A1C ≥6.0 (42 mmol/mol) at 26 and 34 weeks' gestation and with other adverse outcomes with an A1C ≥6.5% (48 mmol/mol).
Association between magnesium status and lipid alterations in pre-dialysis CKD patients   
There exists a strong association between hypomagnesemia and atherogenic dyslipidemia in patients with CKD.
MESA: Association of nonalcoholic fatty liver disease, obesity, and metabolic syndrome, with systemic inflammation and subclinical atherosclerosis   
Nonalcoholic fatty liver disease is associated with increased inflammation and coronary artery calcium independent of traditional risk factors, obesity and metabolic syndrome.
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Impact of atorvastatin and rosuvastatin on renal function in T2DM patients   
Neither treatment with atorvastatin nor rosuvastatin is associated with a significant change in renal function in T2DM patients.
Impact of ranibizumab injections on risk of sustained elevation of intraocular pressure or the need for ocular hypotensive treatment for diabetic macular edema   
Repeated intravitreous injections of ranibizumab may increase the risk of sustained IOP elevation or the need for ocular hypotensive treatment in eyes with center-involved diabetic macular edema and no prior open-angle glaucoma.
Standard early treatmentdiabetic retinopathy study chart and a handheld equivalent in eyes with retinal pathology   
ETDRS chart and handheld device measured acuities are positively and linearly correlated as demonstrated by a correlation coefficient (r) of 0.95.
Predicting diabetes in Diabetes Prevention Program   
Metformin and lifestyle interventions have similar effects in preventing HbA1c-defined diabetes.
Predictive value of peripheral lesions identified on ultrawide field imaging in diabetic retinopathy   
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There exists an association of presence and increasing extent of PPLs with increased risk of diabetic retinopathy progression over 4 years, irrespective of baseline diabetic retinopathy severity and HbA1c levels.
Correlation between peripheral 5-hydroxyindole-3-acetic acid, metabolic syndrome and inflammation   
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An association is revealed between increased 5-HIAA and hsCRP, a marker of chronic low grade inflammation underlying MetS.
The Lipid Paradox: Correlation between serum low-density lipoprotein cholesterol and in-hospital mortality following acute myocardial infarction   
Lowest HDL-C levels are associated with increased in-hospital mortality.
PLANET: Reno-protective effects of atorvastatin and rosuvastatin in diabetics with progressive renal disease   
Atorvastatin seems to have more renoprotective effects than rosuvastatin for the studied chronic kidney disease population.
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Difference in risk of all-cause mortality and vascular events according to gender in patients with T1DM   
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There is roughly 40% greater excess risk of all-cause mortality, and twice the excess risk of fatal and nonfatal vascular events in women than men with type 1 diabetes.
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Outcomes of once-weekly trelagliptin versus daily alogliptin in T2DM patients   
Once-weekly DPP-4 inhibitor trelagliptin showed efficacy and safety, similar to alogliptin once daily in T2DM patients.
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Impact of Veterans Health Administration MOVE! lifestyle change programme in obese patients   
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Participation in the MOVE! programme was associated with weight loss and reduction in incidence of diabetes.
STRIPE: Impact of infancy-onset dietary counseling of low saturated fat   
Repeated infancy-onset dietary intervention effectively prevents MetS in adolescence.
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Persistence of treatment after initiating basal insulin in T2DM patients   
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Type of insulin, antidiabetic co-medication, and patient characteristics influences treatment persistence among T2DM patients initiating basal insulin.
Prevalence of chronic kidney disease in T2DM patients treated in primary care   
Nearly 70% of T2DM patients treated in primary care have some sign of CKD and nearly half of all T2D patients have a significant CKD.
Atherogenic index of plasma and other lipid parameters for assessing risk of T2DM   
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Atherogenic index of plasma can be used as a simple, easily calculated parameter for assessing the risk of T2DM.
IGT Care Call, a telephone based service for people at risk of developing T2DM   
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Telephone services may promote lifestyle changes to prevent type 2 diabetes.
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Peripheral nerve function in asymptomatic patients with type 2 diabetes or latent autoimmune diabetes of adults   
Peripheral nerve dysfunction was common in asymptomatic LADA or T2DM patients.
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Intraocular peroxisome proliferator-activated receptor gamma expression in patients with proliferative diabetic retinopathy   
Anti-VEGF therapy significantly reduces the VEGF concentration (P < 0.0001) but not the PPARγ concentration.
Benefits of linear and undulating periodized strength plus aerobic training in obese adolescents   
Interdisciplinary therapy models that include aerobic plus strength training offered superior effectiveness than only aerobic training in improving lipid profile and insulin sensitivity.
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Diabetes Heart Study: Association of high cardiovascular disease burden in T2DM patients with genetic variants that contribute to CVD   
There is a significant association between increase in genetic risk score and higher levels of coronary artery calcified plaque.
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Correlation between advanced glycation end products, chronic kidney disease and macroangiopathy in T2DM   
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Accumulation of advanced glycation end products is independently associated with renal insufficiency and macroangiopathy in patients with T2D.
Correlation between serum bilirubin concentration and the severity of diabetic retinopathy   
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Serum total bilirubin concentration is negatively associated with increasing severity of retinopathy in T2DM patients.
Pattern of endothelial dysfunction in two vascular territories, the kidney and the brain, affected by diabetic vasculopathic complications   
Glycated peptides are associated with the variability of endothelial dysfunction in the cerebral vessels and the kidney in T2DM.
Augmented insulin and glucose responses during an OGTT are not sufficient to overcome the underlying defects in glucose metabolism in obesity and diabetes   
Hyperglycemia and hyperinsulinemia were not sufficient to compensate for the defect in glucose metabolism in obesity and diabetes.
Adipose tissue content, muscle performance and physical function in obese adults with T2DM and peripheral neuropathy   
%leg intermuscular volume is inversely correlated and %subcutaneous adipose tissue is directly correlated with PPT.
Correlation between neutrophil–lymphocyte ratio and brachial-ankle pulse wave velocity in patients with diabetic retinopathy   
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Neutrophil–Lymphocyte ratio is associated with arterial stiffness in diabetic retinopathy in type 2 diabetes.
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KORA F4 study: Association of CT-pro-vasopressin with T2D, MetS and MetS components   
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Plasma copeptin is associated with type 2 diabetes in men but not in women.
Atherosclerosis Risk in Communities (ARIC) Study: sRAGE, inflammation and risk of atrial fibrillation   
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sRAGE is strongly inversely associated with markers of inflammation at baseline, but not prospectively.
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Health-related quality of life in women and men with T2DM with different treatment regimens
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T2DM treatment has differential impact on physical and mental HRQL and on women and men.
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Temporal sequence of the bidirectional relationship between hyperglycemia and periodontal disease   
A significant bidirectional relationships exists between hyperglycemia and periodontal disease
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Hyperactivation of working memory-related brain circuits in middle-aged newly diagnosed T2DM patients   
HbA1c and brain activations are significantly and positively related to the anterior cingulate cortex and bilateral dorsolateral prefrontal cortex in T2DM patients.
Prevalence of vitamin D deficiency and lack of association with subclinical atherosclerosis in asymptomatic T1DM patients
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T1D patients have lower concentrations and twice more prevalence of 25OHD deficiency than controls.
Prevalence of vitamin D deficiency and lack of association with subclinical atherosclerosis in asymptomatic T1DM patients   
T1D patients have lower concentrations and twice more prevalence of 25OHD deficiency than controls.
HUNT Study: Impact of physical activity and adiposity on cancer risk among diabetics   
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Increased risk of cancer associated with diabetes is confined to individuals with low levels of physical activity, or who are overweight or obese.
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Effects of neighborhood factors and self-care on glycemic control in T2DM adults   
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Self-care behaviors and neighborhood aesthetics had direct effects on glycemic control.
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Cardiovascular safety of insulin secretagogues in T2DM patients following hospitalization for ischemic heart disease   
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In older T2DM patients hospitalized for IHD, prior use of gliclazide, glyburide, or repaglinide seem to be associated with a similar risk of adverse cardiovascular sequelae.
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KORA F4 study: Association of CT-pro-vasopressin with T2D, MetS and MetS components   
Plasma copeptin is associated with type 2 diabetes in men but not in women.
Temporal sequence of the bidirectional relationship between hyperglycemia and periodontal disease
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A significant bidirectional relationships exists between hyperglycemia and periodontal disease.
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Hyperactivation of working memory-related brain circuits in middle-aged newly diagnosed T2DM patients   
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HbA1c and brain activations are significantly and positively related to the anterior cingulate cortex and bilateral dorsolateral prefrontal cortex in T2DM patients.
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The shortwave study: Impact of metabolic syndrome on systolic dysfunction in diabetes
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LV systolic function measured as stress-corrected midwall shortening and mitral annular peak systolic velocity is frequently impaired in T2DM patients without CAD.
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Prevalence of vitamin D deficiency and lack of association with subclinical atherosclerosis in asymptomatic T1DM patients   
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T1D patients have lower concentrations and twice more prevalence of 25OHD deficiency than controls
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Prognostic importance of baseline and serial glycated hemoglobin changes for cardiovascular outcomes   
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Magnitude of HbA1c reduction during the first year of follow-up predicts better cardiovascular outcomes, independent of baseline HbA1c levels.
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Failure to achieve targets of guidelines for prevention and treatment of diabetic complications in T1DM patients
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Failure to reach ADA treatment targets is associated with increased risk of mortality and CVD in patients with type 1 diabetes.
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Correlation between vitamin D status, gender and type 2 diabetes in middle-aged Caucasians
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Low 25(OH)D3serum levels are independently associated with T2DM in women, but not in men.
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Impact of metformin dose and duration of therapy on cobalamin deficiency in T2DM patients on metformin   
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A higher daily and cumulative doses of metformin is strongly associated with lower cobalamin and holotranscobalamin concentrations, while duration is not.
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Predictive ability of plasma levels of various biomarkers of oxidative stress on diabetic neuropathy progression and mortality   
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Oxidative stress predicts progression of peripheral and cardiac autonomic nerve dysfunction over 6 years in diabetic patients.
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Metabolic syndrome in children  
The Harmonious Efficacy of Albiglutide as an Add-On therapy or Monotherapy for an Individualized T2DM Management  
Canagliflozin: The Blockbuster drug for the Co-morbid T2DM treatment  
Dapagliflozin: Clinical perspective   
Treatment and management of diabetic macular edema   
Gestational diabetes mellitus   
From trivial to extremely vital - The resurrection of Metabolic Syndrome for the present Diabetes management  
Lifestyle counseling in routine patient care  
  More..     
 

     

Preventing the development of type I diabetes by targeting TH17 cells: successful results in animal models
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Novo Nordisk's Xultophy® (IDegLira) launched in Switzerland
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UF Health pilot study results lead to national trial of combination treatment for Type 1 diabetes
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