Sep 3, 2014
             
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      Updated: Sep 3, 2014 
Body mass index and visceral adipose tissue together act as predictors of cardiovascular risk factors and outcomes   
Body mass index and visceral adipose tissue together act as predictors of cardiovascular risk factors and outcomes.
Impact of childhood body weight on the risk of hypertension   
Obese youngsters have a risk of hypertension which is six times greater than that observed in normal weights.
ADVANCE-ON: Long term effects of blood pressure lowering in patients with type 2 diabetes   
Reductions in all-cause death and cardiovascular death recorded during active treatment are sustained to the end of post-trial follow-up, but are diminished.
Risk factor for contrast-induced nephropathy after percutaneous coronary intervention   
Metabolic syndrome is a risk factor for contrast-induced nephropathy after percutaneous coronary intervention.
     
ODYSSEY COMBO II: Alirocumab outshines ezetimibe for lowering cholesterol   
Alirocumab significantly improved cholesterol levels compared to ezetimibe, when added to regular statin therapy in patients with high cholesterol and elevated risk of cardiovascular disease (CVD).
ODYSSEY FHI & II: Alirocumab shows lipid-lowering promise in patients with heterozygous familial hypercholesterolaemia   
An investigational lipid-lowering agent called alirocumab produced superior results compared to placebo.
LISTEN: Rosuvastatin versus atorvastatin in lowering cholesterol in T2DM patients   
Rosuvastatin may be a better choice than atorvastatin as cholesterol-lowering statin medications for patients with type 2 diabetes.
Hybrid coronary revascularization versus coronary artery bypass surgery in patients with diabetes mellitus   
When compared to the conventional CABG surgery, hybrid coronary revascularization is associated with less blood product usage and faster recovery.
EURIPE: Glycemic control for kidney injury prevention after PCI   
There is an absolute and percentage significant reduction of serum creatinine after PCI in patients with GIK infusion and NAC administration, in addition to ISS.
Impact of statin therapy on low-density lipoprotein cholesterol and triglyceride levels in patients with hypertriglyceridaemia: A VOYAGER meta-analysis   
LDL-C reduction is substantial and dependent on the choice and dose of statin, in patients with hypertriglyceridemia.
Preventing contrast-induced nephropathy in diabetic patients with chronic kidney disease undergoing coronary interventions   
Single dose administration of erythropoietin prior to coronary angiography or PCI results in trend toward reduction in the incidence of contrast-induced nephropathy.
SMART-MR Study: Correlation between metabolic syndrome, prediabetes, and brain abnormalities in patients with manifest arterial disease   
There exists an association of presence of MetS with smaller brain volume, in patients with manifest arterial disease and even in patients without diabetes.
Impact of metformin versus other antidiabetes medications on risk of cancer   
Diabetics who use metformin have similar risk of developing cancer as those who use sulfonylureas.
Associations of diabetes with β-cell dysfunction and insulin resistance in obese and nonobese women with prior gestational diabetes mellitus   
Among women with prior GDM, β-cell dysfunction show more pronounced contribution to postpartum diabetes in nonobese subjects, while insulin resistance contribute more towards postpartum hyperglycemia among obese subjects.
Boston Puerto Rican Health Study: Association of food-insecure dietary patterns with longitudinal glycemic control in diabetes   
Food insecurity is associated with poor longitudinal glycemic control in diabetes.
Role of osteopontin in complications experienced by patients with type 1 diabetes   
Osteopontin is a strong predictor of incipient diabetic nephropathy, cardiovascular disease, and all-cause mortality in T1DM patients.
Impact of exenatide, sitagliptin, or glimepiride on secretory capacity of β-cell in early type 2 diabetes   
Exenatide or sitagliptin treatment has no significant effect on functional β-cell mass while glimepiride appears to enhance β- and α-cell secretion.
Association of neurocognitive functioning at the time of diagnosis of T1DM with glycemic control after 1 year of diagnosis in children and adolescents   
Deficits in neurocognitive functioning within days of diabetes diagnosis that are associated with diabetes outcomes over 1 year post-diagnosis.
Is the presence of microangiopathy conditional to the development of hyperglycemia-related cerebral compromise   
Ventral striatum, but not cortical volume loss, is related to cognitive dysfunction in T1DM patients with and without microangiopathy.
MAXWEL-CAD Study: Association of rate of weight gain during early adulthood with prevalence of subclinical coronary artery disease in recently diagnosed type 2 diabetes   
Greater rate of prior weight gain may accelerate the subclinical vascular complications development in patients with newly diagnosed T2D.
Impact of telmisartan versus active controls on insulin resistance in hypertensive patients   
Telmisartan significantly improves insulin resistance in patients with hypertension.
Impact of individual mindfulness-based cognitive therapy and cognitive behavior on depressive symptoms among diabetics   
Mindfulness-based cognitive therapy and cognitive behavior therapy individually improve a range of psychological symptoms effectively, in individuals with type 1 and type 2 diabetes.
SAVOR-TIMI 53: Incidence of pancreatitis and pancreatic cancer with saxagliptin   
Risk for pancreatitis in type 2 diabetic patients treated with saxagliptin is low.
St. Carlos Gestational Diabetes Study: Impact of IADPSG criteria for the screening and diagnosis of gestational diabetes mellitus on pregnancy outcomes   
Application of the new IADPSGC is associated with a 3.5-fold increase in prevalence of GDM and also significant improvements in pregnancy outcomes.
Association of Dipeptidyl Peptidase - 4 inhibitors with risk of fracture in type 2 diabetes mellitus patients   
Dipeptidyl Peptidase - 4 inhibitors is not associated with fracture risk fracture compared to controls and to other NIAD users.
Action to Control Cardiovascular Risk in Diabetes Study: Impact of glycemic control on incident atrial fibrillation and outcomes   
Intensive glycemic control does not have any affect on the rate of new-onset atrial fibrillation.
The effect of hyperbaric oxygen therapy on ischemia-modified albumin levels in people with diabetes with foot ulcers   
There is no change in ischemia-modified albumin levels with hyperbaric oxygen therapy in patients with diabetic foot ulcers.
Outcomes of teneligliptin, as an add on treatment in T2DM patients on insulin therapy, with or without other antidiabetes agents   
Add-on treatment with teneligliptin ameliorates glucose fluctuations and improves glycemic control index in patients with type 2 diabetes on insulin therapy.
Malmo preventive project:Correlation between fasting plasma insulin and atrial fibrillation in men   
High levels of fasting plasma insulin are associated with lower risk of incident AF in a middle-aged population.
Association of metabolic syndrome with coronary artery disease based on the presence of diabetes in a symptomatic population   
MetS was independently associated with the presence and severity of CAD only in the non-diabetic subjects.
Efficacy and safety of canagliflozin in T2DM patients   
Canagliflozin improves reduction in glycated hemoglobin A1c levels and body weight with low risk of hypoglycemia.
Effect of GLP-1 receptor agonists on abdominal obesity among type 2 diabetes patients   
Some GLP-1RAs, especially liraglutide-1.8 mg once daily and liraglutide-1.2 mg once daily, significantly reduce waist circumference.
Long-term clinical course of kidney disease in type 1 diabetes   
Intensive diabetes treatment yield durable renal benefits in individuals with type 1 diabetes.
Gender difference in HDL-cholesterol during acute stress   
In patients with diabetes, the gender difference in HDL-C levels is lost at time of admission to hospital but returns when acute stress has resolved.
Glycemic response to microdoses of subcutaneous glucagon at varying levels of insulin   
Endogenous glucose production increases steeply with glucagon doses between 25 and 175 μg at lower insulin infusion rates.
Quality of life and treatment satisfaction in T2DM patients with retinopathy without other major late diabetic complications   
Alcubierre N and colleagues designed this prospective cross-sectional study to assess the influence of retinopathy on quality of life and treatment satisfaction in T2DM patients with no other advanced late complications that could interfere with the outcomes.
Effect of perioperative glycemic control strategy on survival in patients undergoing coronary bypass surgery   
Liberal glycemic control strategy after coronary artery bypass leads to survival rates and improvements in health-related quality of life that are similar to those achieved with a strict target range.
Glitazones do not improve high-density lipoprotein vasorelaxant effect despite increasing HDL cholesterol concentration in type 2 diabetic patients   
HDL remains dysfunctional with impaired antiatherogenic properties.
EVEREST Trial: Use of mineralocorticoid receptor antagonist in hospitalized patients with heart failure, reduced ejection fraction and diabetes mellitus   
Diabetes mellitus does not appear to influence the effectiveness of mineralocorticoid receptor agonist therapy.
Alogliptin versus glipizide in patients with type 2 diabetes mellitus uncontrolled on metformin alone   
Efficacy of alogliptin is sustained over two years in patients with inadequate glycemic control on metformin alone.
Characterization of type 2 diabetes non-remission status following bariatric surgery   
Adjunctive strategies promoting greater fat loss and/or raising adiponectin may serve as key for higher T2D remission rates after bariatric surgery.
Identifying cardiometabolic risk in non-obese individuals   
Waist-to-height ratio can identify cardiometabolic risk in individuals with normal body mass index and waist circumference.
Frequency of lipid coronary plaques in current smokers, former smokers, and nonsmokers   
Current smokers are more likely to have lipid plaques and optical coherence tomography-defined vulnerable plaques.
Outcomes of switching to insulin glargine-based regimens among patient swith T1DM in the real-life setting   
Insulin glargine can be recommended as an effective and safe basal insulin in type 1 diabetes in a real-life setting.
Insulin detemir versus glargine in children with type 1 diabetes mellitus   
Higher insulin detemir doses are required for achieving similar glycemic control as glargine.
Association of human insulin with risk of thyroid cancer in T2DM patients   
Treatment with human insulin does not increase thyroid cancer risk in patients with type 2 diabetes.
Outcomes of adding albiglutide versus insulin lispro in type 2 diabetes inadequately controlled with insulin glargine plus oral agents   
Weekly administration of albiglutide is a simpler therapeutic option than thrice-daily lispro for advancing basal insulin glargine therapy.
Coronary artery bypass graft surgery versus percutaneous coronary intervention newer generation drug-eluting stents in diabetic patients   
Mortality between CABG and PCI using cobalt–chromium everolimus-eluting stent is similar in patients with diabetes mellitus.
Relation of high-density lipoprotein cholesterol:apolipoprotein A-I ratio to progression of coronary atherosclerosis in patients treated with statins   
Increasing levels of HDL-C:apoA-I is associated with less progression of coronary atherosclerosis.
Epicardial adipose tissue volume and coronary artery disease severity in asymptomatic adults with versus without diabetes mellitus   
Increasing volume of epicardial adipose tissue predicts increasing CAD severity even after adjusting for CAC score.
EDITION 1: New insulin glargine 300 units/mL versus glargine 100 units/mL T2DM patients on basal and mealtime insulin   
Gla-300 controls HbA1c as well as Gla-100 in T2DM patients treated with basal and mealtime insulin, with consistently less risk of nocturnal hypoglycemia.
Weight-based insulin glargine dose titration regimen versus glucose level- and current dose-based regimens in T2DM patients that are hospitalized   
The currently proposed weight-based insulin glargine dose titration regimen was effective, tolerable, and user-friendly in achieving FBG target levels in hospitalized patients with hyperglycemia.
Empagliflozin versus glimepiride as add-on to metformin in patients with inadequately controlled type 2 diabetes   
Empagliflozin may serve as an effective and a well tolerated second-line treatment therapy for T2DM patients with inadequate glycaemic control when on metformin.
Correlation of glycemic control with mortality in diabetic patients undergoing percutaneous coronary intervention   
Long-term mortality after percutaneous coronary intervention is significantly higher in diabetic patients not on insulin and with poor glycemic control (HbA1c >10%) versus those with well-controlled diabetes mellitus, as evidenced by HbA1c ≤7%.
Home use of closed-loop insulin delivery for controlling overnight glucose levels in T1DM adults   
Unsupervised overnight closed-loop insulin delivery at home is feasible and can improve glycaemic control in T1DM adults.
DIGAMI 1 trial: Intensified insulin-based glycaemic control after myocardial infarction   
Intensified insulin-based glycaemic control after acute myocardial infarction in patients with diabetes and hyperglycaemia at admission had a long-lasting effect on longevity.
Effects of bariatric surgery in overweight people with T2DM   
Laparoscopic adjustable gastric band surgery in addition with multidisciplinary care, improves glycaemic control with an acceptable adverse event profile in overweight people with type 2 diabetes.
Secondary analysis of the Look AHEAD: Long-term effects of behavioural weight loss interventions on nephropathy in overweight or obese T2DM adults   
Weight loss should be considered as an adjunct to medical treatments in order to prevent or delay progression of CKD.
EPIC-InterAct case-cohort study: Association between saturated fatty acids and type 2 diabetes   
Association of different individual plasma phospholipid saturated fatty acids (SFA) with incident type 2 diabetes in opposite directions suggest that SFAs are not homogeneous in their effects.
Metabolic syndrome in children  
The Harmonious Efficacy of Albiglutide as an Add-On therapy or Monotherapy for an Individualized T2DM Management  
Canagliflozin: The Blockbuster drug for the Co-morbid T2DM treatment  
Dapagliflozin: Clinical perspective   
Treatment and management of diabetic macular edema   
Gestational diabetes mellitus   
From trivial to extremely vital - The resurrection of Metabolic Syndrome for the present Diabetes management  
Lifestyle counseling in routine patient care  
  More..     
 

     

Bayer Receives EU Approval for EYLEA® in Diabetic Macular Edema    
U.S. FDA approves INVOKAMET™ (canagliflozin/metformin HCl) for treating adults with type 2 diabetes    
US FDA approves Afrezza, a rapid-acting inhaled insulin in diabetic adults    
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EASD - European Association for the Study of Diabetes, 2014
Sep 15, 2014 - Sep 19, 2014.
Vienna, Austria


    

 


 
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